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Bakuchiol

Also called Bakuchiol
Depends on the product Rating confidence Moderate evidence Solid evidence, not yet settled.
Personal care

In plain terms

A plant compound from the seeds of Psoralea corylifolia, marketed as a gentle, natural alternative to retinol. Purified bakuchiol is well tolerated and works a lot like retinol on skin. The catch is which form is in the bottle, because some products labeled this way use a raw seed extract that carries sun-reactive compounds.

What the evidence shows

Bakuchiol is the active that turned a traditional seed into a skincare trend, and in purified form it earns its reputation: clinical work puts it close to retinol for smoothing and tone, with less of the dryness and flaking. Natural does not settle the safety question, though, and here the source plant matters. Psoralea corylifolia seeds and the surrounding plant parts contain furocoumarins, the same class of sun-reactive compounds found in some citrus, which can cause blistering and lasting pigment changes when treated skin meets UV light. A purified bakuchiol isolate removes these; a crude Psoralea corylifolia seed extract or oil does not, and some products sold as bakuchiol are in fact that cruder material. The molecule itself is not free of questions. Bakuchiol shows estrogen-like activity in lab assays, and at high oral doses in animals it has caused liver damage, which is part of why the traditional ingested form has a hepatotoxicity record. Those are oral, high-dose findings, not what a few percent on the face delivers, and there is no evidence of liver or hormone effects from topical cosmetic use. What that leaves is a real, product-dependent split: a purified topical formula is gentle, while a crude extract version brings a genuine sun-reactivity risk.

On the label

Listed as Bakuchiol if it is the purified compound. The one to check for is Psoralea Corylifolia Seed Extract or Psoralea Corylifolia Seed Oil, sometimes sold under the bakuchiol name, which can carry the sun-reactive furocoumarins purified bakuchiol leaves out. Either way, daytime sunscreen is sensible.

Commonly found in

Anti-aging serumRetinol-alternative creamNight moisturizerNatural skincare
Sources: J Cosmetic Dermatology · Phytochemistry Reviews · Frontiers in Pharmacology
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